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A new strategy for the synthesis of the core trisaccharide of asparagine-linked sugar chains

✍ Scribed by Ichiro Matsuo; Megumi Isomura; Richard Walton; Katsumi Ajisaka

Book ID: 104255830
Publisher: Elsevier Science
Year: 1996
Tongue: French
Weight: 208 KB
Volume: 37
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(96)02034-5

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✦ Synopsis

The core trisacchande common to all asp~ragine-linked glycopmtein oligosaccharides was synthesized using two novel processes: I) regioselective acetylation using lipase, and 2) inversion of the C-2 hydroxyl group of the glucose residue in a glucosyl chitobiose derivative to produce the corresponding mannosyl chitobiose derivative.

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