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A New Strategy for the Construction of Polycycles Bearing a Nitrogen Atom on the Ring Fusion.

โœ Scribed by Reynald Deleens; Arnaud Gautier; Serge R. Piettre


Publisher
John Wiley and Sons
Year
2010
Weight
34 KB
Volume
33
Category
Article
ISSN
0931-7597

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ChemInform Abstract: New Strategy for th
โœ M. LAUTENS; E. FILLION ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 34 KB ๐Ÿ‘ 2 views

The substituted dioxacyclic compounds (III) and (XI) are synthesized via the inter-and intramolecular "pincer" Diels-Alder reaction. The first ring-opening reaction of these compounds is significantly faster than the second. Treatment of tetracycle (IV) with BuLi at higher temperatures provides the