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A new strategy for prenatal diagnosis of homozygous α0-thalassemia

✍ Scribed by K. Y. Leung; C. Liao; Q. M. Li; S. Y. Ma; M. H. Y. Tang; C. P. Lee; V. Chan; Y. H. Lam

Book ID
112224292
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
78 KB
Volume
28
Category
Article
ISSN
0960-7692

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✍ Ivy S. L. Ng; Joyce B. K. Ong; Cheng Lim Tan; Hai Yang Law 📂 Article 📅 1994 🏛 Springer 🌐 English ⚖ 359 KB

The strategy for early prenatal diagnosis of [3thalassemia in Singapore by direct detection of the mutant 13-globin gene requires the spectrum of mutations producing the disorder in this population to be characterized. We analyzed 134 13-thalassemia alleles from Singapore by specific oligonucleotide