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A new site-selective route for synthesis of functionalized imidazo[2,1-c][1,2,4]triazoles

โœ Scribed by Ahmad S. Shawali; Magda A. Abdallah; Mosselhi A. N. Mosselhi; Mahmoud S. Elewa

Publisher
Journal of Heterocyclic Chemistry
Year
2007
Tongue
English
Weight
287 KB
Volume
44
Category
Article
ISSN
0022-152X

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โœฆ Synopsis

Abstract

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Reactions of 4โ€arylhydrazonoโ€2โ€methylthioโ€imidazolinโ€5(1__H__)โ€one 3 with various hydrazonoyl halides 1 proved to be siteโ€selective and yielded the respective imidazo[2,1โ€c][1,2,4]triazole derivatives 8. The structure of the latter was elucidated by Xโ€ray analysis and the mechanism of the studied reactions was discussed.

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