1-Alkyl-B-carbolines were treated with dialkyl oxalates to give N-alkylated canthin-alkaloid derivatives in one step During the reproduction of the experiments described by Atta-ur-Rahman 1) we found that the reaction of 1-alkyl-8-carbolines (1) with excess dialkyl oxalates (2) between 155-175'C fo
β¦ LIBER β¦
A new simple procedure for alkylation of nitrogen heterocycles using dialkyl oxalates and alkoxides.
β Scribed by Jan Bergman; Peter Sand
- Book ID
- 104241337
- Publisher
- Elsevier Science
- Year
- 1984
- Tongue
- French
- Weight
- 183 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
β¦ Synopsis
A variety of nitrogen heterocycles are -alkylated in high yields with dialkyl oxalates and potassium alkoxides in refluxing dimethylformamide.
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