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A new simple method for the synthesis of cyclobutyl cyanide

✍ Scribed by Shlomo Cohen; Gadi Rothenberg; Yoel Sasson

Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
125 KB
Volume
39
Category
Article
ISSN
0040-4039

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✦ Synopsis

A clean and efficient intramolecular cyclization of 5-halovaleronitrile to cyclobutyl cyanide was achieved using NaOH and phase-transfer catalysts in a solid-liquid system at 70 Β°C.

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