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A New Selective Approach to 1,1-Bis(silyl)-2-arylethenes and 1,1-Bis(silyl)-1,3-butadienes via Sequential Silylative Coupling—Heck Coupling Reactions.

✍ Scribed by Piotr Pawluc; Grzegorz Hreczycho; Bogdan Marciniec


Publisher
John Wiley and Sons
Year
2007
Weight
30 KB
Volume
38
Category
Article
ISSN
0931-7597

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Total Synthesis of (+)-Alexine by Utiliz
✍ Martina Dressel; Per Restorp; Peter Somfai 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 294 KB 👁 1 views

## Abstract A novel route towards the polyhydroxylated pyrrolizidine alkaloid (+)‐alexine has been developed. A key step in this synthesis is a highly stereoselective [3+2] annulation reaction of __N__‐Ts‐α‐amino aldehyde **7 a** (Ts=tosyl) and 1,3‐bis(silyl)propene **8 a** for the construction of