𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A new route to α-trifluoromethyl-α,β-unsaturated esters

✍ Scribed by Xingang Zhang; Feng-Ling Qing; Yonggang Yang; Jiang Yu; Xiang-Kai Fu


Publisher
Elsevier Science
Year
2000
Tongue
French
Weight
120 KB
Volume
41
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

✦ Synopsis


The treatment of α-bromo-α,β-unsaturated esters with FSO 2 CF 2 CO 2 Me and CuI in DMF/HMPA constitutes a new synthetic scheme for the preparation of α-trifluoromethyl-α,β-unsaturated esters.


📜 SIMILAR VOLUMES


A new sequential defluorination route to
✍ Hiroshi Hata; Takeshi Kobayashi; Hideki Amii; Kenji Uneyama; John T. Welch 📂 Article 📅 2002 🏛 Elsevier Science 🌐 French ⚖ 284 KB

a-Fluoro-a,b-unsaturated ketones were prepared from trifluoromethyl ketones via a sequence involving Mg metal promoted successive double defluorination. Trifluoromethyl ketones were transformed to b,b-difluoroenol silyl ethers which were then coupled with aldehydes and ketones to b-hydroxy-a,a-diflu