A new method for the construction of the AB-ring core of Taxol was developed utilizing a new skeletal transformation protocol as a pivotal step. The acid-catalyzed rearrangement of the cyclopentenone-allene photoadduct gave a bridged seven-membered ketone, which was easily transformed, using the int
β¦ LIBER β¦
A new route to spiroacetals and the construction of a model for the synthesis of phyllanthocin
β Scribed by Karen R. Biggs; Philip J. Parsons; David J. Tapolzcay; J. Mark Underwood
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- French
- Weight
- 105 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
β¦ Synopsis
A new route to spiroacetals is presented which relies on a tin mediated radical cyclisation. This reaction has been applied to a model for phyllanthocin construction.
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