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A New Route to Furanoeremophilane Sesquiterpenoids. Synthesis of (.+-.)-6β-Hydroxyeuryopsin.

✍ Scribed by M. Sundaram Shanmugham; James D. White


Publisher
John Wiley and Sons
Year
2004
Weight
128 KB
Volume
35
Category
Article
ISSN
0931-7597

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✍ Stéphanie Fréville; Philippe Delbecq; Vu Moc Thuy; Huguette Petit; Jean Pierre C 📂 Article 📅 2001 🏛 Elsevier Science 🌐 French ⚖ 85 KB

A new diastereoselective synthesis of 2,6-disubstituted piperidinic alkaloids is presented. Three natural compounds, the (-)-pinidinone 1a, the (+)-dihydropinidine 1b and the (-)-pinidinol 1c were prepared from optically pure (6R)-6-methylpiperidin-2one 2. This method is based on the chemo-and diast