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A new route to 1,2,4- triazoles and 1,3,4- thiadiazoles from 1-acylbithiourea

✍ Scribed by Tadashi Okawara; Yoshihiro Tateyama; Tetsuo Yamasaki; Mitsuru Furukawa


Book ID
112128986
Publisher
Journal of Heterocyclic Chemistry
Year
1988
Tongue
English
Weight
186 KB
Volume
25
Category
Article
ISSN
0022-152X

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1,2,4-Triazoles. Improved synthesis of 5
✍ Francesco Paolo Invidiata; Giancarlo FurnΓ‘; Ilaria Lampronti; Daniele Simoni πŸ“‚ Article πŸ“… 1997 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 243 KB

## Abstract The reaction of thiocarbohydrazide with carboxylic acids at the melting temperature allows an improved preparation of the S‐substituted 4‐amino‐3‐mercapto‐1,2,4‐triazole heterocycles. The crude 4‐amino‐5‐mercapto‐1,2,4‐triazoles react easily with carboxylic acids or carboxylic acid chlo