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A new route to 1-oxygenated carbazoles. Synthesis of murrayafoline-a

โœ Scribed by Tracey Martin; Christopher J. Moody


Book ID
104229093
Publisher
Elsevier Science
Year
1985
Tongue
French
Weight
113 KB
Volume
26
Category
Article
ISSN
0040-4039

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โœฆ Synopsis


l-Oxygenated carbazoles are prepared in four steps from indole-2-carboxylates by Claisen condensation with butyrolactones, followed by hydrolysis with concomitant decarboxylation, oxidation, and ring closure (Scheme 2); the route is applied to the synthesis of the carbazole alkaloid, murrayafoline-A.


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