A new radioiodine exchange labeling technique
β Scribed by H.-J. Sinn; H.H. Schrenk; W. Maier-Borst
- Book ID
- 103919716
- Publisher
- Elsevier Science
- Year
- 1986
- Weight
- 456 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0883-2889
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β¦ Synopsis
A new technique of radioiodine exchange labeling is presented. The method was developed with respect to the short physical half lives of 123I and 121I, the altered activity concentrations and varying impurities, which hamper the previously introduced labeling methods. The described "one step reaction" is applicable to a series of organic compounds with different physicochemical and physiological behaviour as well as to all radioisotopes of iodine.
π SIMILAR VOLUMES
In our search for a platelet-specific labeling agent, metaraminol (MA), a low-toxic pharmaceutical for the treatment of hypotension and cardiogenic shock, attracted our attention. Its active incorporation and accumulation by platelets have been recognized. At first, the preparation of 125I radioiodi