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A new polymorphic and multicopy MHC gene family related to nonmammalian class I

✍ Scribed by Chanvit Leelayuwat; David C. Townend; Mariapia A. Degli-Esposti; lawrence J. Abraham; R. L. Dawkins

Publisher
Springer-Verlag
Year
1995
Tongue
English
Weight
33 KB
Volume
41
Category
Article
ISSN
0093-7711

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The human major histocompatibility complex (MHC) region is a genomic region spanning about 4000 kilobases (kb) including the class I, class II, and class III subregions. The class I subregion is larger than the two others but with fewer genes described to date. It includes a) classical human leucocy

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## Abstract __Mill__ (MHC class I‐like located near the leukocyte receptor complex) is a novel family of class I genes identified in mice that is most closely related to the human __MICA/B__ family. In the present study, we isolated __Mill__ cDNA from rats and carried out a comparative genomic anal