A New One-Step Synthesis of Maleimides by Condensation of Glyoxylate Esters with Acetamides. -A series of disubstituted maleimides (17 derivatives) is synthesized by one-pot condensation of a glyoxylate with acetamides. A mechanism is proposed.
โฆ LIBER โฆ
A new one step synthesis of maleimides by condensation of glyoxylate esters with acetamides
โ Scribed by Margaret M. Faul; Leonard L. Winneroski; Christine A. Krumrich
- Book ID
- 104260557
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- French
- Weight
- 206 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0040-4039
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Whereas condensation of 2-methyl-3-nitrobenzoate esters with dimethylformamide dimethyl acetal gives 5-nitroisocoumarin, analogous condensation with dimethylacetamide dimethyl acetal proceeds via a different route, affording 1-methoxy-3dimethylamino-5-nitronaphthalene in good yield. Extension of the