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A new ‘one-pot’ synthesis of hydrazides by reduction of hydrazones

✍ Scribed by Dario Perdicchia; Emanuela Licandro; Stefano Maiorana; Clara Baldoli; Clelia Giannini


Publisher
Elsevier Science
Year
2003
Tongue
French
Weight
359 KB
Volume
59
Category
Article
ISSN
0040-4020

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✦ Synopsis


A new, high-yielding methodology for reducing hydrazones to hydrazines is described, which allows the synthesis of different mono-, di-and trisubstituted hydrazines. Moreover, the reduction step can be followed by an in situ reaction with a carboxylic acid making possible a 'one-pot' synthesis of trisubstituted hydrazides. The method is relatively general and, in principle, suitable for industrial applications.


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