## Abstract A pair of new oleanane‐type nortriterpene saponin epimers, neogypsoside A (**1**) and B (**2)** (__Fig. 1__) with neogypsogenin A (**3**) and neogypsogenin B (**4**) as the two new aglycons, as well as the two known triterpene saponins **5** and **6** __(Fig. 1__), were isolated from th
A New Nortriterpene from the Root of Celastrus hypoleucus
✍ Scribed by Hong Wang; Xuan Tian; Guo Qing Ying
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- German
- Weight
- 182 KB
- Volume
- 93
- Category
- Article
- ISSN
- 0018-019X
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✦ Synopsis
Abstract
A new nortriterpene, 2‐hydroxy‐3‐methyl‐21‐oxo‐12,24‐dinor‐D : B‐friedooleana‐1,3,5(10),7‐tetraen‐29‐oic acid (1), was isolated from the root of Celastrus hypoleucus, together with the two known compounds, celastorol (2) and pristimerine (3). Their structures were elucidated on the basis of spectroscopic analyses. Compounds 1–3 exhibited in vitro significant antioxidant (against lipid peroxidation; by the TBARS method) and antitumor activities (against cancer cell lines P‐388, A‐549, HL‐60, and BEL‐7402).
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