A new mutation in the bovine insulin-like growth factor binding protein-3
β Scribed by A Haegeman; A Van Zeveren; L J Peelman
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 402 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0268-9146
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π SIMILAR VOLUMES
Insulin-like growth factors (IGFs) are potent mitogens involved in the regulation of cell proliferation and apoptosis. The action of IGFs is mediated through a specific cell membrane receptor (IGF-IR), and the interactions between IGFs and this receptor are regulated by IGF-binding proteins (IGFBPs)
## Abstract Recent epidemiological studies have shown that high serum levels of insulinβlike growth factorβI (IGFβI) are associated with an increased risk of lung, colon, breast and prostate cancer. Since very few studies have addressed the role of serum levels of IGFβI in the development of pancre