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A new multidrug reinduction protocol with topotecan, vinorelbine, thiotepa, dexamethasone, and gemcitabine for relapsed or refractory acute leukemia

โœ Scribed by Kolb, E A; Steinherz, P G


Book ID
110055627
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
100 KB
Volume
17
Category
Article
ISSN
0887-6924

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Background. The outcome of patients with acute myeloid leukemia (AML) who relapse or fail to achieve an initial remission has been dismal. Procedure. Fifteen pediatric patients with AML, 4 relapsed and 11 primary refractory, were reinduced with a loading bolus of 0.5 g/m 2 cytarabine (ara-C) followe