A new model of peritoneal carcinomatosis in rats obtained by transplantation of a 20 methylcholanthrene (20 MCA) induced fibrosarcoma

Localization and invasion by a soft tiss

Localization and invasion by a soft tissue tumor induced by pellets made of hydroxypropylcellulose mixed with 20-methylcholanthrene in the femur of rats

✍ Nobuyuki Yoshida; Tomihisa Koshino; Takamiti Morii; Yoji Nagashima 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 589 KB

Background. Pellets made of a carcinogenic substance, methylcholanthrene, admixed with a high molecular weight substance, hydroxypropylcellulose, were implanted into the thigh of 90 rats (three groups, 30 rats each). In Group 1, the pellets were placed at the window made in the cortex of the lfemur