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A new model for monitoring the kinetics of calcium binding to the sarcoplasmic reticulum Ca2+-ATPase employing the flash-photolysis of caged-calcium

✍ Scribed by Laura J. DeLong; Charles M. Phillips; Jack H. Kaplan; Antonio Scarpa; J. Kent Blaise


Book ID
118388005
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
357 KB
Volume
21
Category
Article
ISSN
0165-022X

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We present a model for predicting the temporal and spatial dependence of [Ca] in the cardiac subsarcolemmal diadic region (cleft), following Ca release from the "feet" of the sarcoplasmic reticulum. This region is modeled as a disc 10 nm thick, 430 nm in radius, with or without Ca binding sites and