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A New Model for Bacterial Growth in Heterogeneous Systems

✍ Scribed by B.P. Hills; K.M. Wright

Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
539 KB
Volume
168
Category
Article
ISSN
0022-5193

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✦ Synopsis

A general theory of spatially dependent bacterial growth in heterogeneous systems is developed by combining a structured-cell kinetic model of bacterial metabolism with reaction-diffusion equations describing the transport of nutrients in the growth medium. Rate constants in the theory are determined for Listeria monocytogenes by fitting the viable count batch growth data acquired in homogeneous, shake-flask cultures. The rate constants are then used to calculate the form of bacterial growth when it occurs as localized microcolonies in structured systems. The same theory is used to analyse the effects of transient variations in environmental variables.

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