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A new mode of transcriptional repression by c-myc: methylation

✍ Scribed by Gartel, A L

Book ID
110070135
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
70 KB
Volume
25
Category
Article
ISSN
0950-9232

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## Abstract The p27^Kip1^ (p27) cyclin‐dependent kinase inhibitor and c‐Myc oncoprotein play essential roles in control of cell cycle progression and apoptosis. Induction of __p27__ (__CDKN1B__) gene transcription by Forkhead box O proteins such as FOXO3a leads to growth arrest and apoptosis. Previ