Testing for Hardy-Weinberg equilibrium (HWE) is used routinely as an important initial step for genotype data quality checking. Departure from HWE can be caused by many factors, such as genotyping errors, population stratification, and disease association, if we use affected individuals only. In a s
β¦ LIBER β¦
A new method of testing for Hardy-Weinberg equilibrium and ordering populations
β Scribed by Nader Ebrahimi; Bilgili Devrim
- Book ID
- 107584955
- Publisher
- Indian Academy of Sciences
- Year
- 2007
- Tongue
- English
- Weight
- 141 KB
- Volume
- 86
- Category
- Article
- ISSN
- 0022-1333
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## Abstract Testing HardyβWeinberg equilibrium (HWE) in the control group is commonly used to detect genotyping errors in genetic association studies. We propose a likelihood ratio test for testing HWE in the study population using both case and control samples. This test incorporates underlying as
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