A New Method for the Synthesis of Substituted Indeno[1,2-b]thiophene with Subsequent Ring Expansion to Form Substituted Thieno[3,2-c]quinoline.

A new method for the synthesis of substi

A new method for the synthesis of substituted indeno[1,2-b]thiophene with subsequent ring expansion to form substituted thieno[3,2-c]quinoline

✍ Lyle W. Castle; Tarek Abou Elmaaty 📂 Article 📅 2006 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 204 KB 👁 1 views

## Abstract magnified image 2‐Phenacylindan‐1,3‐dione (**3**) was treated with Lawesson's reagent (2,4‐bis(4‐methoxyphenyl)‐1,3‐dithia‐2,4‐diphosphetane‐2,4‐disulfide) to form 2‐phenyl‐4__H__‐indeno[1,2‐__b__]thiophene‐4‐one (**4**). Compound **4** was subsequently reacted with hydroxyl amine to f