A new method for the synthesis of bicyclic pyran acetals
β Scribed by Duygu Ergunes; Volkan Kumbaraci; Bekir Karliga; Naciye Talinli
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 2007
- Tongue
- English
- Weight
- 253 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0022-152X
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β¦ Synopsis
Abstract
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cisβFused bicyclic acetals were obtained from the unusual cyclization reaction between diols and dihydropyran. Furothiopyran, substituted pyranopyrans, and pyranooxepine and pyranobenzoxepine compounds were obtained with high diastereoselectivity and cisβdiastereomers were obtained in high yields.
π SIMILAR VOLUMES
Two new methods for the synthesis of orthoesters and compounds containing an orthoester moiety (dihydroisoxazoles) are presented. Mixed orthoesters of general formulas RC(OR 1 )(OR 2 ) 2 and RC(OR 1 )-(OR 2 )(OR 3 ) were prepared via addition of ROH (R = Bu or m-methylphenyl) to O-allyl acetals (acr
Since a large and growing number of natural products have been shown to contain fused cyclic acetals, such as furo [2,3-b]furans, as part structures [1] and since many of them have a variety of activities (e.g., antitumor, antimicrobial, and insect antifeedant), interest has rapidly grown and result