Halo-Nitro Derivatives. -Use of wet basic alumina as support for Oxone (KHSO 5 ) and KBr is crucial for the conversion of oximes (I), (III), (V), and (VII) directly into the corresponding gem-bromo-nitro compounds. -
β¦ LIBER β¦
A new method for the one-step conversion of oximes into gem-halo-nitro derivatives
β Scribed by Massimo Curini; Francesco Epifano; Maria Carla Marcotullio; Ornelio Rosati; Monia Rossi
- Book ID
- 108379335
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- French
- Weight
- 372 KB
- Volume
- 55
- Category
- Article
- ISSN
- 0040-4020
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Two tin@) complexes, Sn(SPhh-and Sn(C4H406)g2-. besides NaHSo3. are involved in a procedure developed for the rapid transfmation at pH 5-6 of R-CHZ-NO2 into R-CHOH-S03Na. from which the de&d aldehydes have been isdated in 80-91% overall yields. llms, a new ahemative to the Nef maction is now in hand