A New Method for the Generation of Titanium(III) Complexes and its Application in Pinacol Coupling Reactions

✍ Scribed by Christoph Alexander Knoop; Armido Studer

• Publisher: John Wiley and Sons
• Year: 2005
• Tongue: English
• Weight: 80 KB
• Volume: 347
• Category: Article
• ISSN: 1615-4150
• DOI: 10.1002/adsc.200505180

✦ Synopsis

Abstract

A new method for the in situ generation of various Ti(III) complexes is presented. Cyclohexadienyl‐Ti(IV) derivatives, which are readily prepared from the corresponding lithiated cyclohexadienes, afford the corresponding Ti(III) complexes upon thermal CTi‐bond homolysis. The Ti(III) compounds generated using this novel method have successfully been used in the reductive dimerization of benzaldehyde. In particular, TiBr~3~, TiCp~2~Cl and Ti(O‐__i‐__Pr)~3~ have been generated via this approach. Moreover, the method also offers an entry to new chiral Ti(III) complexes as documented by the preparation of Ti(III)CpTADDOLate.