Development of an in vitro cell culture
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Youngtae Hong; Seung Shin Yu; Nam-Kyung Yoon; Sung June Kang; Jun-Tae Lee; Sujeo
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Article
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2008
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John Wiley and Sons
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English
β 305 KB
π 1 views
## Abstract ## Background The use of retroviral vectors has shown an actual clinical benefit in a few inherited diseases. However, the occurrence of cases of leukemia after the XβSCID gene therapy trial raised concerns about the safety of insertional mutagenesis inherent to the biology of the retr