𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A new method for proton detection of H217O with potential applications for functional MRI

✍ Scribed by Itamar Ronen; Gil Navon

Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
444 KB
Volume
32
Category
Article
ISSN
0740-3194

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

A method is presented for the sensitive detection of minute amounts of H~2~^17^O. The method is based on the increase of the T~2~ of the water protons following an irradiation of the ~17~O resonance frequency, due to the partial or full decoupling of the ^1^H‐^17^O spin‐spin interaction. It is demonstrated that when ^17^O concentrations are low, full decoupling is achieved, and at short echo times the increase in the amplitude of the proton echo signal is proportional to the ^17^O content of the sample. The potential of the method for indirect ^17^O imaging is substantiated by a simple one dimensional projection of cylindrical phantoms containing various ^17^O concentrations. Using interleaved sequences with and without ^17^O decoupling, errors due to time dependent effects are minimized.

πŸ“œ SIMILAR VOLUMES

Detection of 17O-tagged phosphate by 31P
Detection of 17O-tagged phosphate by 31P MRS: A method with potential for in vivo studies of phosphorus metabolism
✍ Peter E. Thelwall πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 222 KB

## Abstract We present a method for MR detection of ^17^O‐labeled phosphate groups. The method employs the __T__~2~ relaxivity effect of ^17^O on ^31^P nuclei to distinguish between ^17^O‐labeled and unlabeled phosphate groups, and uses spin‐echo (SE) acquisitions with RF decoupling at the ^17^O fr

A new HPLC method with fluorescence dete
A new HPLC method with fluorescence detection for the determination of memantine in human plasma
✍ SΔ±dΔ±ka E. Toker; Olcay SağırlΔ±; Sevil M. Γ‡etin; Armağan Γ–nal πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 138 KB πŸ‘ 1 views

## Abstract A sensitive, selective, simple and fast HPLC method based on the formation of derivative with fluorescamine was developed for the determination of memantine (ME) in human plasma. Separation was achieved on a CN column (200 mmΓ—4.6 mm) using acetonitrile–10 mM orthophosphoric acid contain