A new method for determining sulfoxides in peptide molecules using x-ray photoelectron spectroscopy

✍ Scribed by Derek Jones; Giuseppe Disteffano; Claudio Toniolo; Gian Maria Bonora

• Publisher: Wiley (John Wiley & Sons)
• Year: 1978
• Tongue: English
• Weight: 541 KB
• Volume: 17
• Category: Article
• ISSN: 0006-3525
• DOI: 10.1002/bip.1978.360171116

✦ Synopsis

Abstract

The problem of the quantitative determination of sulfoxide groups in peptide molecules has been re‐examined. The approaches currently available for the estimation of δ‐sulfoxide amino acids are limited in number and characterized by serious shortcomings; in addition, the choice of methods for the estimation of γ‐sulfoxide amino acids is even more restricted. A new, rapid, and nondestructive direct method for determining quantitatively all types of sulfoxides in peptide molecules by using x‐ray photoelectron spectroscopy is described.