A new method for detecting single nucleotide polymorphism using GFP-display
β Scribed by Takashi Aoki; Keiko Satoh; Tomoko Imamura; Hiroyuki Watabe
- Book ID
- 116616162
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 200 KB
- Volume
- 60
- Category
- Article
- ISSN
- 0165-022X
No coin nor oath required. For personal study only.
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ecules which partially or completely lack the GC clamp (data not shown). PCR amplicons using these primers are indistinguishable from others produced with HPLC-purified oligonucleotides (Fig. 1A, compare lanes 1-4 with 5-8). However, the heterogeneity of PCR products produced with contaminated prime
## Abstract Multiple testing is a challenging issue in genetic association studies using large numbers of single nucleotide polymorphism (SNP) markers, many of which exhibit linkage disequilibrium (LD). Failure to adjust for multiple testing appropriately may produce excessive false positives or ov