✦ LIBER ✦

A new lung model: An investigation with the aid of a digital computer

✍ Scribed by G.Richard Kelman

Publisher: Elsevier Science
Year: 1970
Tongue: English
Weight: 400 KB
Volume: 3
Category: Article
ISSN: 0010-4809
DOI: 10.1016/0010-4809(70)90058-3

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✦ Synopsis

The properties of a new lung model, based on the assumption that ventilation and perfusion in the pulmonary alveoli are log-normally distributed, have been investigated with the aid of an ICL 4/50 digital computer. The behaviour of this model agrees well with established ideas in respiratory physiology, and predicted values of the oxygen, carbon dioxide and nitrogen alveolar-to-arterial tension differences accord with experimentally determined values in the literature. It is suggested that this model may prove valuable in clinical and physiological research; it permits the quantification of abnormalities of pulmonary function in terms of the parameters of the patient's hypothetical log-normal alveolar frequency distribution. rather as they are at present quantified in terms of such hypothetical parameters as "physiological dead space" and "percentage pulmonary venous admixture."

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