A new group of synthetic polymers with antitumor activity
✍ Scribed by R. Bierling; G. D. Wolf; B. Bömer
- Publisher
- Springer
- Year
- 1980
- Tongue
- English
- Weight
- 210 KB
- Volume
- 67
- Category
- Article
- ISSN
- 0028-1042
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Despite improvements in the treatment and prevention of cancer, the number of new diagnoses continues to rise; this has fuelled substantial interest in the development of new and effective chemotherapeutic agents. Compounds of the triazene class, such as dacarbazine, have been used in t
BMY-28175 is a novel antitumor antibiotic produced in fermentation by Actinomadura verrucosospora. The cytotoxic effects of BMY-28175 were determined using murine and human tumor cell lines in vitro. Following 72 hour exposure, the drug had IC50 values 1.5 to 13.5 ng/ml in a microtiter assay. BMY-28