A New Group of Plant-Derived Naphthoquinone Pesticides

✍ Scribed by Khambay, Bhupinder P. S.; Batty, David; Beddie, David G.; Denholm, Ian; Cahill, Matthew R.

• Publisher: John Wiley and Sons
• Year: 1997
• Tongue: English
• Weight: 228 KB
• Volume: 50
• Category: Article
• ISSN: 1526-498X
• DOI: 10.1002/(sici)1096-9063(199708)50:4<291::aid-ps604>3.0.co;2-8

✦ Synopsis

A series of compounds with structures based on insecticidal/acaricidal naphthoquinones isolated from Calceolaria andina has been synthesised. A feature of the series is the lack of resistance shown by strains resistant to established classes of pesticides. The importance for activity of the tetra-substituted carbon atom in the side-chain, as observed in the natural products, has been investigated. In analogues with acyclic side-chains the position of the tetrasubstituted carbon for optimum activity was dependent on the length of the sidechain. With cyclic side-chains, activity was dependent on the size of the ring, the number and position of the substituents therein. Activity of the compounds examined was particularly high against Bemisia tabaci and T etranychus urticae in direct-contact tests, but was much lower than expected in leaf-dip tests. A partial improvement based on formulation has been demonstrated.