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A new genome type of adenovirus 3 associated with severe lower acute respiratory infection in children

✍ Scribed by Adriana E. Kajon; Patricia Murtagh; Susana Garcia Franco; Maria Cecilia Freire; Mercedes C. Weissenbacher; Dr. Jorge Zorzópulos


Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
495 KB
Volume
30
Category
Article
ISSN
0146-6615

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✦ Synopsis


Abstract

Adenovirus 3 was found associated with ten cases of infantile lower acute respiratory infection in patients aged 2–18 months. Of these, five had a fatal outcome, with severe lung damage. Restriction enzyme analysis with Bam HI, Bcl I, BgI II, Bst E II, Hind III, Sal I, Sma I, Xba I, and Xho I revealed the presence of the same genome type in all ten specimens. The genomic variant was different from those previously reported for serotype 3 and therefore was tentatively denominated 3f.


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✍ Adriana E. Kajon; Manuela Vicente Suarez 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 430 KB

## Abstract Genome analysis was performed on 69 adenovirus isolates from pharyngeal secretions of young children hospitalized with severe lower acute respiratory disease in Santiago, Chile, between 1984 and 1986. As expected, most isolated strains belonged to subgenus B (68.1%). Among the isolates