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A New-Generation Stable Inducible Packaging Cell Line for Lentiviral Vectors

✍ Scribed by Farson, Deborah; Witt, Rochelle; McGuinness, Ryan; Dull, Tom; Kelly, Michael; Song, Jinping; Radeke, Robert; Bukovsky, Anatoly; Consiglio, Antonella; Naldini, Luigi

Book ID
120226979
Publisher
Mary Ann Liebert
Year
2001
Tongue
English
Weight
607 KB
Volume
12
Category
Article
ISSN
1043-0342

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πŸ“œ SIMILAR VOLUMES

Development and characterization of a mi
Development and characterization of a minimal inducible packaging cell line for simian immunodeficiency virus-based lentiviral vectors
✍ Seraphin Kuate; Ralf Wagner; Klaus Überla πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 250 KB

## Abstract ## Background Lentiviral vectors allow gene transfer into non‐dividing cells. Further development of these vector systems requires stable packaging cell lines that enable adequate safety testing. ## Methods To generate a packaging cell line for vectors based on simian immunodeficienc

Generation of a packaging cell line for
Generation of a packaging cell line for prolonged large-scale production of high-titer HIV-1-based lentiviral vector
✍ Yajin Ni; Susan Sun; Ibe Oparaocha; Laurent Humeau; Brian Davis; Reuben Cohen; G πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 573 KB

## Abstract ## Background An Erratum has been published for this article in Journal of Gene Medicine 7(6), 2005, 835. A stable packaging cell line facilitates large‐scale lentivirus vector manufacture. However, it has been difficult to produce clinical‐scale HIV‐1‐based lentiviral vectors using