A new free radical-based method for the synthesis of spiroannulated medium rings

✍ Scribed by Wei Zhang; Paul Dowd

• Publisher: Elsevier Science
• Year: 1992
• Tongue: French
• Weight: 187 KB
• Volume: 33
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)92068-9

✦ Synopsis

Free radical promoted cyclobutanone ring expansion provides a new entry to a variety of spiroannulated ring systems. Direct methods of spiroannulation starting from alkene precursors, particularly those suitable for the preparation of medium rings, are limited in number. This makes it attractive to