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A New Family of Macrocycles Produced by Sequential Claisen—Schmidt Condensations

✍ Scribed by Luke T. Higham; Ulf P. Kreher; Colin L. Raston; Janet L. Scott; Christopher R. Strauss


Publisher
John Wiley and Sons
Year
2004
Weight
12 KB
Volume
35
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

For Abstract see ChemInform Abstract in Full Text.


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ChemInform Abstract: A New, Stereoselect
✍ A. R. WHEILDON; D. W. KNIGHT; M. P. LEESE 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 31 KB 👁 2 views

I) and addition of nitrones (II) results in a smooth condensation to give the unsaturated hydroxylamines (III) stereoselectively. These undergo reverse-Cope cyclizations at room temperature leading to the diastereomeric mixture of pyrrolidine-N-oxides (IV) and (V). -