Considerable evidence is gathering for the involvement of vascular endothelial growth factor (VEGF) in the vascularization and growth of primary tumours as well as in the formation of metastases. The expression of VEGF depends on activated oncogenes and inactivated tumour suppressor genes as well as
A New Era for Cancer Treatment: Gold-Nanoparticle-Mediated Thermal Therapies
β Scribed by Laura C. Kennedy; Lissett R. Bickford; Nastassja A. Lewinski; Andrew J. Coughlin; Ying Hu; Emily S. Day; Jennifer L. West; Rebekah A. Drezek
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 824 KB
- Volume
- 7
- Category
- Article
- ISSN
- 1613-6810
No coin nor oath required. For personal study only.
β¦ Synopsis
Abstract
Nanotechnologyβbased cancer treatment approaches potentially provide localized, targeted therapies that aim to enhance efficacy, reduce side effects, and improve patient quality of life. Goldβnanoparticleβmediated hyperthermia shows particular promise in animal studies, and early clinical testing is currently underway. In this article, the rapidly evolving field of gold nanoparticle thermal therapy is reviewed, highlighting recent literature and describing current challenges to clinical translation of the technology.
π SIMILAR VOLUMES