A new diterpenoid with labdane skeleton

✍ Scribed by L. Canonica; B. Rindone; C. Scolastico; G. Ferrari; C. Casagrande

• Publisher: Elsevier Science
• Year: 1968
• Tongue: French
• Weight: 218 KB
• Volume: 9
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)89575-1

✦ Synopsis

In spite of the close botanical analogy with Marrubium vulgare, Marrubium incanum (collected in Jugoslavia) contains only a very small quantity of marrubiin.

After chromatography of the acetone extract on silica-gel we isolated, together with small quantities of other diterpenoids and several flavanoids, a crystalline substance (I). C20H2605, m.p. 172-173", [a]: +480 (c=l% in CH OH), 3 x max 212 ml (~=10300), 290 mp (~<100), as the most abundant terpenoid constituent. The physical properties of I correspond with those described by L. A. Salei, D.P. Popa and G. V. Lazur'evskiy (1) for peregrinine, a compound isolated from Marrubium peregrinum, which possesses the same molecular formula but whose structure has not been elucidated.