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A New Cytotoxic Diterpene with the Dolabellane Skeleton from the Marine Sponge Sigmosceptrella quadrilobata

โœ Scribed by Valeria Costantino; Ernesto Fattorusso; Alfonso Mangoni; Massimo Di Rosa; Angela Ianaro; Maurice Aknin; Emil M. Gaydou

Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
97 KB
Volume
1999
Category
Article
ISSN
1434-193X

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โœฆ Synopsis

A new diterpene with the dolabellane skeleton 1 has been absolute stereochemistry, was performed with the aid of MS, NMR, and CD data and by molecular modeling. Compound isolated from the sponge of the Indian Ocean, Sigmosceptrella quadrilobata. Its structure elucidation, including 1 is moderately cytotoxic against four tumor cell lines.

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