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A New Cyclopeptide from Clausena anisum-olens

✍ Scribed by Yun-Song Wang; Hong-Ping He; Jing-Hua Yang; Yue-Mao Shen; Jun Zhou; Xiao-Jiang Hao

Publisher
John Wiley and Sons
Year
2005
Tongue
German
Weight
56 KB
Volume
88
Category
Article
ISSN
0018-019X

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✦ Synopsis

A new cyclopeptide, clausenain I (1), has been isolated by a multi-step chromatography procedure from Clausena anisum-olens. Its structure was elucidated as cyclo (-Gly 1 -Ile 2 -Ile 3 -Val 4 -Leu 5 -Ile 6 -Ile 7 -Leu 8 -Leu 9 -) by extensive 2D-NMR spectroscopic methods and chemical evidence. It is the first time that a natural cyclic peptide has been isolated from the genus Clausena.

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