A New Convergent Route to Conduritols A−F from a Common Chiral Building Block
✍ Scribed by Kadota, Kohei; Takeuchi, Miwako; Taniguchi, Takahiko; Ogasawara, Kunio
- Book ID
- 126910357
- Publisher
- American Chemical Society
- Year
- 2001
- Tongue
- English
- Weight
- 57 KB
- Volume
- 3
- Category
- Article
- ISSN
- 1523-7060
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📜 SIMILAR VOLUMES
Starting from a common man-made chiral sugar building block, five out of eight L-aldohexoses have been synthesized in a diastereocontrolled manner to complete an integrated synthesis of the eight possible aldohexoses; the remaining three L-hexoses were synthesized from the same building block. Thus,
Synthesis of the versatile F sugar unit building block of moenomycin A, Phenyl 2-O-levulinoyl-4-C-methyl-l-thio-13-D-glucopyranosiduronic acid is described starting from phenyl l-thio-13-Dgalactopyranoside. The key synthetic steps included: (I) Regioselective protection of the 3-OH group of phenyl 6