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A New Complex Translocation (15;20;17)(q22;p13;q21) in Acute Promyelocytic Leukemia

✍ Scribed by Katsuya Yamamoto; Hiroyuki Hamaguchi; Kaoru Nagata; Masaru Kobayashi; Teruyuki Takashima; Masafumi Taniwaki

Book ID
114136321
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
709 KB
Volume
101
Category
Article
ISSN
0165-4608

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Two new 3β€² PML Breakpoints in t(15;17)(q
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✍ MarΓ­a C. ChillΓ³n; Marcos GonzΓ‘lez; RamΓ³n GarcΓ­a-Sanz; Ana Balanzategui; David Go πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 208 KB

In the present article, two new types of PML/RARA junctions are described. Both were identified in diagnostic samples from two t(15;17)(q22;q21)-positive acute promyelocytic leukemia (APL) patients who failed to achieve complete remission. By using different sets of primers, reverse transcriptase po