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A new classification of generalized carcinoma of the breast based on response to therapy

✍ Scribed by Dr. Dennis V. Razis


Publisher
John Wiley and Sons
Year
1976
Tongue
English
Weight
304 KB
Volume
8
Category
Article
ISSN
0022-4790

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✦ Synopsis


Abstract

Classifications of generalized carcinoma of the breast were based up to now on factors of definitely proven prognostic significance. These classifications are very useful in defining prognosis, but they help only to a limited extent in selecting treatment. We are proposing a new classification of three groups for generalized carcinoma of the breast according to objective response to therapy: to (a) responders, (b) nonresponders, and (c) patients with static disease. It is pointed out that in some cases there is discrepancy between prognosis and response to therapy, as some patients with β€œpoor prognosis” respond dramatically to treatment while others with β€œgood prognosis” do not respond to any type of treatment and treatment is actually harmful. It is also pointed out that our classificaiton has a dynamic meaning, as a patient can switch from one group to another. The proposed classification might be of more help in deciding the therapeutic management.


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