A New Class of Potent Vascular Endothelial Growth Factor Receptor Tyrosine Kinase Inhibitors: Structure−Activity Relationships for a Series of 9-Alkoxymethyl-12-(3-hydroxypropyl)indeno[2,1- a ]pyrrolo[3,4- c ]carbazole-5-ones and the Identification of CEP-5214 and Its Dimethylglycine Ester Prodrug Clinical Candidate CEP-7055

✍ Scribed by Gingrich, Diane E.; Reddy, Dandu R.; Iqbal, Mohamed A.; Singh, Jasbir; Aimone, Lisa D.; Angeles, Thelma S.; Albom, Mark; Yang, Shi; Ator, Mark A.; Meyer, Sheryl L.; Robinson, Candy; Ruggeri, Bruce A.; Dionne, Craig A.; Vaught, Jeffry L.; Mallamo, John P.; Hudkins, Robert L.

• Book ID: 120353322
• Publisher: American Chemical Society
• Year: 2003
• Tongue: English
• Weight: 414 KB
• Volume: 46
• Category: Article
• ISSN: 0022-2623
• DOI: 10.1021/jm0301641