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A New Class of Hormonally Active Steroids

✍ Scribed by REERINK, E. H.; SCHÖLER, H. F. L.; WESTERHOF, P.; QUERIDO, A.; KASSENAAR, A. A. H.; DICZFALUSY, E.; TILLINGER, K. C.

Book ID
109607703
Publisher
Nature Publishing Group
Year
1960
Tongue
English
Weight
215 KB
Volume
186
Category
Article
ISSN
0028-0836

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## Incubation of 6u-fluoro-Reichstein's Compound 3'" (I) and its A'-analog (IV) with bovine adrenals followed by acetylation led to 6c4uorohydrocortisone acetate (II) and 6a-fluoroprednisolone acetate (III) respectively. Selenium dioxide oxidation of II also afforded III. Chromium trioxide oxidati