A new chromogenic substrate for γ-glutamyl transpeptidase
✍ Scribed by Anders Persson; Irwin B. Wilson
- Publisher
- Elsevier Science
- Year
- 1978
- Tongue
- English
- Weight
- 346 KB
- Volume
- 89
- Category
- Article
- ISSN
- 0003-2697
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Many carcinomas in humans are rich in gamma-glutamyl transpeptidase (GGT), a plasma membrane enzyme that reacts with extracellular substrates. Thus, biochemical targeting of chemotherapeutic agents may be achieved by converting anticancer drugs into their gamma-glutamyl derivatives. Chemical convers
## Abstract In a study of the development of a strong inhibitor for γ‐glutamyl transpeptidase (γ‐GTP), the inhibitory effect of 21 arylboronic acids was determined in the γ‐GTP‐mediated hydrolysis of __N__‐(L‐γ‐glutamyl)‐4‐nitroanilide. It was shown that most boronic acids can moderately inhibit th