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A New Catalyst for a Pd Catalyzed Alder Ene Reaction. A Total Synthesis of (+)-Cassiol

✍ Scribed by Trost, Barry M.; Li, Yong


Book ID
121409346
Publisher
American Chemical Society
Year
1996
Tongue
English
Weight
473 KB
Volume
118
Category
Article
ISSN
0002-7863

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A formal total synthesis of (Β±)-anatoxin
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nonane skeleton 3a was prepared by intramolecular aminocarbonylation of 2a catalyzed by palladium. In three steps 3a was transformed into 8 which had previously been transfomled into anatoxin-a, thus completing the formal total synthesis.